October 1, 2018
The SHAPE-MaP technology developed in the lab of Dr. Weeks identifies functional motifs within RNA by mapping the RNA three-dimensional structure. By using three-dimensional RNA structure, the platform enables targeting of thousands of previously undruggable RNAs, expanding the druggable genome by 60-fold. Structures acquired from this platform will be used to develop small molecules that bind functional and therapeutically relevant regions of RNA.
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