Portfolio
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Clearside Biomedical
- Clinical-stage ophthalmic pharmaceutical company with pivotal trial planned for initiation in late 2013
- Scientific founders: Dr. Mark Prasunitz at Georgia Tech and Dr. Henry Edelhauser at Emory
- Clearside’s proprietary, disruptive microinjection platform delivers drug through the suprachoroidal space (“SCS”), providing drug to the diseased area of the retina to treat sight-threatening diseases
- Procedure has been tested for safety/tolerability in the clinic as the only office-based, non-surgical drug delivery to the SCS
- Funded in January 2012, management efficiently used capital to advance from preclinical development to first clinical trial in less than 1 year
- Hatteras holds 2 board seats including Board Chair
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G1 Therapeutics, Inc.
- Innovative, scientifically-robust platform of novel, potent and selective CDK4/6 inhibitors to protect bone marrow from chemotherapy and ionizing radiation
- Scientific founders: Dr. Ned Sharpless at UNC and Dr. Kwok Kim-Wong at Dana-Farber/Harvard
- Awarded over $4M in NIH funding to date in addition to funding through the North Carolina Biotechnology Center
- Funded in August 2012, investment will accelerate pre-clinical timeline by 1 year, providing financing toward lead molecule selection and pre-IND enabling work
- Hatteras holds 2 board seats, including Executive Chair
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Coferon
- Creating molecules with highly tunable structures to increase drug-like properties to treat unmet and undermet medical needs
- Scientific founders: Dr. Francis Barany and Dr. Maneesh Pingle at Weill-Cornell Medical College and Dr. Don Bergstrom at Purdue University
- CEO is Colin Goddard, PhD, former CEO of OSI Pharma and member of the Hatteras Discovery Portfolio Review Committee
- Funded in June 2012
- Hatteras holds one board seat